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Decreased gastrointestinal toxicity associated with a novel capecitabine schedule (7 days on and 7 days off): a systematic review

PCS6422

March 30, 2016

Cadoo KA, Gajria D, Suh E, Patil S, Theodoulou M, Norton L, Hudis CA, Traina TA.

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Eniluracil plus 5-fluorouracil and leucovorin: treatment for metastatic breast cancer patients in whom capecitabine treatment rapidly failed

PCS6422

November 1, 2013

Rivera E, Chang JC, Semiglazov V, Burdaeva O, Kirby MG, Spector T.

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A possible cause and remedy for the clinical failure of 5-fluorouracil plus eniluracil

PCS6422

January 1, 2010

Spector T, Cao S.

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Uridine phosophorylase: an important enzyme in pyrimidine metabolism and fluoropyrimidine activation

PCS6422

May 1, 2004

Cao D, Pizzorno G.

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Pharmacokinetic and pharmacodynamic effects of oral eniluracil, fluorouracil and leucovorin given on a weekly schedule

PCS6422

July 1, 2003

Guo XD, Harold N, Saif MW, Schuler B, Szabo E, Hamilton JM, Monahan BP, Quinn MG, Cliatt J, Nguyen D, Grollman F, Thomas RR, McQuigan EA, Wilson R, Takimoto CH, Grem JL.

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Impact of two weekly schedules of oral eniluracil given with fluorouracil and leucovorin on the duration of dihydropyrimidine dehydrogenase inhibition

PCS6422

May 1, 2002

Keith B, Guo XD, Zentko S, Harold N, Schuler B, Quinn M, Shapiro J, Grem JL.

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Randomized, open-label, phase III study of a 28-day oral regimen of eniluracil plus fluorouracil versus intravenous fluorouracil plus leucovorin as first-line therapy in patients with metastatic/advanced colorectal cancer.

PCS6422

March 15, 2002

Schilsky RL, Levin J, West WH, Wong A, Colwell B, Thirlwell MP, Ansari RH, Bell WN, White RL, Yates BB, McGuirt PV, Pazdur R.

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Phase I and pharmacokinetic trial of weekly oral fluorouracil given with eniluracil and low-dose leucovorin to patients with solid tumors

PCS6422

December 1, 2000

Grem JL, Harold N, Shapiro J, Bi DQ, Quinn MG, Zentko S, Keith B, Hamilton JM, Monahan BP, Donavan S, Grollman F, Morrison G, Takimoto CH.

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Pharmacology of fluorinated pyrimidines: eniluracil

PCS6422

November 1, 2000

Baker SD.

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Preclinical development of eniluracil: enhancing the therapeutic index and dosing convenience of 5-fluorouracil

PCS6422

November 1, 2000

Paff MT, Baccanari DP, Davis ST, Cao S, Tansik RL, Rustum YM, Spector T.

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