Annual report pursuant to Section 13 and 15(d)

License Agreements (Details Narrative)

v3.24.1
License Agreements (Details Narrative) - USD ($)
12 Months Ended
May 17, 2022
Jun. 16, 2021
Oct. 06, 2020
Aug. 23, 2020
Aug. 19, 2020
Mar. 19, 2018
Dec. 31, 2023
Dec. 31, 2022
Jan. 25, 2024
Jan. 22, 2024
Jan. 21, 2024
Common stock, shares issued             1,291,000 806,774      
Stock Issued During Period, Value, New Issues             $ 6,352,077        
CoNCERT Pharmaceuticals, Inc [Member] | License Rights [Member]                      
Stock Issued During Period, Shares, Acquisitions           14,931          
Stock Issued During Period, Value, New Issues           $ 8,000,000.0          
Subsequent Event [Member]                      
Common stock, shares issued                   1,291,000 24,706,474
License Agreement [Member] | Subsequent Event [Member]                      
Common stock, shares issued                 5,000    
License Agreement [Member] | Elion Oncology [Member]                      
Common Stock, Capital Shares Reserved for Future Issuance       5,000              
Expense and related liability $ 189,000                    
Performance of milestone conditions, description       including dosing a first patient with a product in a Phase 2 or 3 clinical trial within 48 months from when we entered into the License Agreement. We are currently on track to dose our first patient in a Phase 2 clinical trial on or before October 2, 2024. Either party may terminate the agreement in the event of a material breach of the agreement that has not been cured following written notice and a 90-day opportunity to cure such breach (which is shortened to 15 days for a payment breach).              
Stock Issued During Period, Shares, Acquisitions               5,000      
License Agreement [Member] | Elion Oncology [Member] | First Milestone [Member]                      
Milestone payment description       shares of our common stock on each of the first and second anniversary dates of the Elion License Agreement.              
License Agreement [Member] | Ocuphire Pharma Inc [Member]                      
Stock Issued During Period, Shares, Acquisitions   2,235                  
Cash paid under license agreement   $ 200,000                  
Liabilities Assumed   $ 66,583                  
License Agreement [Member] | Aposense, Ltd. [Member]                      
Stock Issued During Period, Shares, Acquisitions     31,250                
Milestone payments, description     As additional consideration, we will pay Aposense development and regulatory milestone payments (up to $3.0 million per milestone) upon the achievement of certain milestones, which primarily consist of having a drug indication approved by a regulatory authority in the United States or another country. In addition, we will pay Aposense one-time sales milestone payments based on the achievement during a calendar year of one or more thresholds for annual sales for products made and pay royalties based on annual licensing sales. We are also required to split any sales milestone payments or royalties we receive with Aposense based on any sub-license agreement we may enter.                
License Agreement [Member] | Aposense, Ltd. [Member] | Maximum [Member]                      
Development and regulatory milestone payments     $ 3,000,000.0                
License Agreement [Member] | Yuhan Corporation [Member]                      
Performance of milestone conditions, description         specific diligence milestones that consist of: (i) preparing a first draft of the product development plan within 90 days; (ii) requesting an FDA pre-IND meeting for a product within 6 months; (iii) dosing a first patient in a Phase 2A clinical trial with a product within 24 months; and (iv) dosing a first patient with a product in a Phase 2B clinical trial, Phase 3 clinical trial or other pivotal clinical trial with a product by August 19, 2024.            
Stock Issued During Period, Shares, Acquisitions         25,000            
Milestone payments, description         In addition, we must pay Yuhan one-time sales milestone payments based on the achievement during a calendar year of one or more thresholds for annual sales for products made and pay royalties based on annual licensing sales. We are also required to split any milestone payments received with Yuhan based on any sub-license agreement we may enter.            
License Agreement [Member] | Yuhan Affiliate [Member] | Underwritten Public Offering [Member] | October 2020 [Member]                      
Shares issued in connection with our 2020 offering     37,500                
Proceeds from offering     $ 3,000,000