Processa Pharmaceuticals, Inc.

7380 Coca Cola Drive, Suite 106,

Hanover, Maryland 21076

November 7, 2018

VIA EDGAR

United States Securities and Exchange Commission

Division of Corporation Finance

100 F Street, NE

Washington, D.C. 20549

Attention: Ms. Dorrie Yale

	Re:	Processa Pharmaceuticals, Inc.
		Registration Statement on Form S-1 (Registration No. 333-226428)

Ladies and Gentlemen:

Pursuant to Rule 461 under the Securities Act of 1933, as amended, the undersigned registrant, Processa Pharmaceuticals, Inc. (the “Registrant”), hereby requests acceleration of effectiveness of its above-referenced Registration Statement to 4:30 P.M., Eastern time, on November 9, 2018, or as soon as practicable thereafter. The Registrant respectfully requests that you notify Neda Sharifi of Foley & Lardner LLP of such effectiveness by a telephone call to (904) 359-8719.

	Very truly yours,

	Processa Pharmaceuticals, Inc.

	By:	/s/ David Young
		David Young, Pharm.D., Ph.D.
		Chief Executive Officer